Donor Oocyte / Donor Sperm Programme

Donor Oocyte / Donor Sperm Programme


Donor sperm / oocyte programme is alternative treatment offered to infertile couples who fail to conceive with their own gametes.

Who needs this sperm donation:

  • A male partner with absence sperm in the ejaculate / testes.
  • A male  partner with a genetic  abnormalities.
  • A male partner with severe low count and abnormal sperms.

Sperm Donation:

It is a process by which the donor gives ejaculated semen sample for donation.  It is cryopreserved labeled and used when required.   It is an anonymous process.  Only the physical characteristics of donor are available for selection.

Egg donation:

The donor is given gonadotrophin injection to stimulate her ovaries to produce multiple eggs.  These are retrieved, fertilized with the sperm of the husband or donor.  The resulting embryo is transferred to the recipient’s uterus.  It is again and anonymous process where both the donor and recipient  are double blinded.

Who might need egg donation?

  • Older women with poor quality oocytes
  • Women who cannot use their own oocytes due to poor quality or herediatary diseases.
  • Women who have repeatedly failed to become pregnant through in-vitro fertilization.
  • Women with ovarian failure from ovarian surgery, premature ovarian failure or menopause.
  • Chromosomal abnormalities in the women and the embryos
  • Repeated miscarriages.

How are the sperms and eggs screened for donations?

Some basic screening is required for the donation of sperms or oocytes.  There can even be some guidelines mentioned by local governments:

  • Age – Most of the clinics would set a certain age limit for the donors.  Also, the eggs of women have been seen to be more fertile when they are young.
  • Physical exam – Samples of blood and urine are taken to look for infectious diseases, like HIV.  In the case of sperms, they are cryopreserved to be tested again after an interval of six months before  the donor can be accepted .
  • Genetic testing – A blood sample is analyzed to ensure that the donors do not carry any genetic condition.  Some clinics go through much more rigorous testing than others.
  • Family medical history-Details need to be provided about the medical history of two previous generations in the family.  A hereditary disease would disqualify the donors.
  • Personal and sexual history - The donors are required to share their sexual history and other personal information to ensure that they do not have the risk factors of developing an infectious disease.  Education, hobbies and other interests of the donors are also noted.

Assisted reproductive technologies are quite advanced these days and the  couples can only consider the option of donated gametes after repeated failures. The doctor would be the best person to ask for guidance or alternatives.



Authored by Dr. Radhika Meka

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